Triethylamine → HCID 178469368, 화합물
반응식
C(N(CC)CC)C.Cl.[CH:9]([NH2:11])=[NH:10].[C:12]([C:19](OCC)=[O:20])#[C:13][C:14]([O:16][CH2:17][CH3:18])=[O:15]>C(#N)C>[OH:20][C:19]1[N:11]=[CH:9][N:10]=[C:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:12]=1참가 물질
5
반응 조건
- 온도
- 50 °C
실험 절차
Triethylamine (17.3 mL) was added dropwise to a solution of formamidine hydrochloride (10.0 g) and diethyl acetylenedicarboxylate (19.9 mL) in acetonitrile (300 mL) at room temperature. The reaction mixture was stirred at 50° C. for 1 hr and heated under reflux overnight. The solvent of the reaction mixture was evaporated under reduced pressure to give a crude product of the title compound as a brown solid. This compound was used for the next step without further purification.
후처리
- temperatureheated
- temperatureunder reflux overnight
- customThe solvent of the reaction mixture was evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-619edd9f62cc41ebac78a59eded74a31
- 출처 데이터셋
- uspto-grants-2016_07
- 특허 번호
- US09382188B2
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