L-Alaninol → N-((S)-2-Hydroxy-1-(4-methoxyphenyl)ethyl)-3-(tetrahydrofuran-3-ylamino)isoquinoline-6-carboxamide

반응식

N[C@@H:2]([CH3:5])[CH2:3][OH:4].[NH2:6][CH:7]1[CH2:11][CH2:10][O:9][CH2:8]1.Cl.FC1C=[C:16]([C@@H:22]([C:24]2C=N[N:27]([CH3:29])[CH:28]=2)N)[CH:17]=[CH:18]C=1OC.Cl.[NH2:31][C@@H:32]([C:35]1[CH:40]=[CH:39][C:38]([O:41][CH3:42])=[CH:37][CH:36]=1)[CH2:33][OH:34]>>[OH:34][CH2:33][C@@H:32]([NH:31][C:3]([C:2]1[CH:5]=[C:22]2[C:16](=[CH:17][CH:18]=1)[CH:29]=[N:27][C:28]([NH:6][CH:7]1[CH2:11][CH2:10][O:9][CH2:8]1)=[CH:24]2)=[O:4])[C:35]1[CH:40]=[CH:39][C:38]([O:41][CH3:42])=[CH:37][CH:36]=1