Dichloromethane → 4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}piperidine

반응식

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][CH2:15][c:16]2[c:17](-[c:24]3[c:25]([Cl:31])[cH:26][cH:27][cH:28][c:29]3[Cl:30])[n:18][o:19][c:20]2[CH:21]2[CH2:22][CH2:23]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:39][CH2:40][Cl:41].[OH:32][C:33]([C:34]([F:35])([F:36])[F:37])=[O:38]>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][CH2:15][c:16]2[c:17](-[c:24]3[c:25]([Cl:31])[cH:26][cH:27][cH:28][c:29]3[Cl:30])[n:18][o:19][c:20]2[CH:21]2[CH2:22][CH2:23]2)[CH2:12][CH2:13]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 59369325Tert-butyl 4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidine-1-carboxylate

생성물 1

HCID 593693344-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}piperidine

출처 및 근거

ORD 기록: ord-bfad5a7284634e1b875c494a4969edd8
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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