2-Pyrrolidin-1-ylmethyl-piperidine → 4,9-Dihydro-4-[[2-[(1-pyrrolidinyl)methyl]-1-piperidinyl]-acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one

반응식

[Cl:1][CH2:2][C:3](=[O:4])[N:5]1[c:6]2[c:7]([cH:17][s:18][cH:19]2)[C:8](=[O:16])[NH:9][c:10]2[c:11]1[cH:12][cH:13][cH:14][cH:15]2.[N:20]1([CH2:25][CH:26]2[NH:27][CH2:28][CH2:29][CH2:30][CH2:31]2)[CH2:21][CH2:22][CH2:23][CH2:24]1>>[CH2:2]([C:3](=[O:4])[N:5]1[c:6]2[c:7]([cH:17][s:18][cH:19]2)[C:8](=[O:16])[NH:9][c:10]2[c:11]1[cH:12][cH:13][cH:14][cH:15]2)[N:27]1[CH:26]([CH2:25][N:20]2[CH2:21][CH2:22][CH2:23][CH2:24]2)[CH2:31][CH2:30][CH2:29][CH2:28]1

참가 물질

반응물 2

HCID 27605412-Pyrrolidin-1-ylmethyl-piperidine

HCID 200638994-chloroacetyl-9,10-dihydro-4H-thieno[3,4-b][1,5]benzodiazepin-10-one

생성물 1

HCID 135785694,9-Dihydro-4-[[2-[(1-pyrrolidinyl)methyl]-1-piperidinyl]-acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one

출처 및 근거

ORD 기록: ord-9572db3f2afb474796851d483aa363d0
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…