3-(Trifluoromethyl)aniline → 4-Pyridinecarboxamide, 2-bromo-N-[3-(trifluoromethyl)phenyl]-

반응식

[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][N:10]=1)[C:5]([OH:7])=O.[F:11][C:12]([F:21])([F:20])[C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][CH:19]=1)[NH2:16]>>[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][N:10]=1)[C:5]([NH:16][C:15]1[CH:17]=[CH:18][CH:19]=[C:13]([C:12]([F:11])([F:20])[F:21])[CH:14]=1)=[O:7]

참가 물질

반응물 2

HCID 73753-(Trifluoromethyl)aniline

HCID 2227012-Bromoisonicotinic acid

생성물 1

HCID 866958424-Pyridinecarboxamide, 2-bromo-N-[3-(trifluoromethyl)phenyl]-

실험 절차

In a manner similar to that described in Preparation 17, 2-bromoisonicotinic acid and 3-trifluoromethylaniline were converted to the title compound

출처 및 근거

ORD 기록: ord-03b6a03d81134fcaad717b3426f1bcba
출처 데이터셋: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09388176B2

반응 노트

불러오는 중…