Methanesulfonyl chloride → HCID 90102825, 화합물

HRID 1052576노트

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HRID 1052576 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([CH:9]([F:11])[F:10])[CH:8]=1)[NH2:5].[CH3:12][S:13](Cl)(=[O:15])=[O:14]>>[Br:1][C:2]1[CH:3]=[C:4]([NH:5][S:13]([CH3:12])(=[O:15])=[O:14])[CH:6]=[C:7]([CH:9]([F:10])[F:11])[CH:8]=1

참가 물질

3

반응물 2

HCID 31297Methanesulfonyl chlorideHCID 584563863-Bromo-5-(difluoromethyl)aniline

생성물 1

HCID 90102825HCID 90102825, 화합물수율 104.6%

실험 절차

3-Bromo-5-(difluoromethyl)aniline (876 mg, 3.95 mmol) was treated with methanesulfonyl chloride (458 μl, 5.92 mmol) according to the method described in Preparation 15b to give 1.24 g (100% yield) of the title compound. Purity 95%.

출처 및 근거

ORD 기록
ord-565550346483494c92e56000051fa0d0
출처 데이터셋
uspto-grants-2016_07
특허 번호
US09388189B2

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