Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Cyanide → 2-(3-Cyanopropyl)-5-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzofuran
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Cyanide | HCID 8929 | — |
| 반응물 | 3-[5-(5-Methyl-2-phenyl-4-oxazolylmethoxy)-2-benzofuranyl]propanol | HCID 19694374 | — |
| 생성물 | 2-(3-Cyanopropyl)-5-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzofuran | HCID 19694364 | 80% |
반응 단계
In the same manner as in Example 13, 3-[5-(5-methyl-2-phenyl-4-oxazolylmethoxy)-2-benzofuranyl]propanol was mesylated and then reacted with sodium cyanide to yield 2-(3-cyanopropyl)-5-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzofuran (yield 80%), which was then recrystallized from acetone-isopropyl ether to yield colorless prisms having a melting point of 114° to 115° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05723479 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-667e2aee4c9a4838b14ae6bea3b0b581 |
| 출처 메모 | uspto-grants-1998_03 |