HCID 10516606, 화합물 → HCID 89699678, 화합물

반응식

[CH2:1]([O:3][CH:4]([O:18][CH2:19][CH3:20])[CH2:5][N:6]1[C:10]([NH2:11])=[CH:9][C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:7]1)[CH3:2].Br[C:22]1[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[C:24]([F:31])[C:23]=1[CH3:32]>>[F:31][C:24]1[C:23]([CH3:32])=[C:22]([NH:11][C:10]2[N:6]([CH2:5][CH:4]([O:18][CH2:19][CH3:20])[O:3][CH2:1][CH3:2])[N:7]=[C:8]([C:12]3[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=3)[CH:9]=2)[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=1

참가 물질

반응물 2

HCID 10516606HCID 10516606, 화합물

HCID 542079842-Bromo-6-fluoro-4-nitrotoluene

생성물 1

HCID 89699678HCID 89699678, 화합물

실험 절차

Analogously to Example 13A/Step 1, 1.5 g (5.43 mmol) of the compound of Example 4A and 1.4 g (5.97 mmol) of 1-bromo-3-fluoro-2-methyl-5-nitrobenzene gave 1.19 g (50% of theory) of the title compound.

출처 및 근거

ORD 기록: ord-86f95affd21a4df38832f5ad95cffbdd
출처 데이터셋: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09394309B2

반응 노트

불러오는 중…