3-Methoxy-5-(pentafluoro-lambda6-sulphanyl)benzoic acid → 3-Methoxy-N-{4-methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-5-(penta-fluoro-lambda6-sulphanyl)benzamide
반응식
[CH3:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[N:9]1[C:16]2[N:12]([N:13]=[C:14]([C:17]3[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=3)[CH:15]=2)[CH:11]=[CH:10]1.[CH3:23][O:24][C:25]1[CH:26]=[C:27]([CH:31]=[C:32]([S:34]([F:39])([F:38])([F:37])([F:36])[F:35])[CH:33]=1)[C:28](O)=[O:29]>>[CH3:23][O:24][C:25]1[CH:26]=[C:27]([CH:31]=[C:32]([S:34]([F:39])([F:35])([F:36])([F:37])[F:38])[CH:33]=1)[C:28]([NH:6][C:5]1[CH:7]=[CH:8][C:2]([CH3:1])=[C:3]([N:9]2[C:16]3[N:12]([N:13]=[C:14]([C:17]4[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=4)[CH:15]=3)[CH:11]=[CH:10]2)[CH:4]=1)=[O:29]참가 물질
3
실험 절차
30 mg (0.10 mmol) of the compound of Example 6A and 29 mg (0.10 mmol) of the compound of Example 25A were reacted and worked up analogously to the procedure of Example 16. This gave 32 mg (55% of theory) of the title compound.
출처 및 근거
- ORD 기록
- ord-ca88e15fd3b94704bbdeb0b6b3212d63
- 출처 데이터셋
- uspto-grants-2016_07
- 특허 번호
- US09394309B2
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