참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phosphorus oxybromide | HCID 24613 | — |
| 반응물 | 8-Bromo-1,2-dihydroquinolin-2-one | HCID 10933094 | — |
| 생성물 | 2,8-Dibromoquinoline | HCID 45925951 | 64% |
반응 단계
A mixture of phosphorus oxybromide (1.59 g, 5.55 mmol) and 8-bromo-2(1H)-quinolinone (0.250 g, 1.11 mmol) was heated at 125° C. for 2 h before being poured onto ice. The resulting precipitate was filtered and crystallized from MeOH to give 2,8-dibromo-quinoline (0.2 g, 64%) as colorless prisms. MS (ESI, pos. ion) m/z: 287.8 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09394297B2 |
|---|
| 출처 데이터셋 | uspto-grants-2016_07 |
|---|
| ORD ID | ord-6e9d9aa5f6fb4a3eb57a0be875163924 |
|---|
| 출처 메모 | uspto-grants-2016_07 |
|---|
