Bupivacaine (USAN:INN:BAN) → Ephedrine

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[CH3:1]CCCN1C(C(NC2C(C)=CC=CC=2C)=O)CCCC1.[CH3:22][NH:23][CH2:24][C@H:25]([OH:34])[C:26]1[CH:27]=[CH:28][C:29](O)=[C:30](O)[CH:31]=1>>[CH3:1][C@H:24]([NH:23][CH3:22])[C@H:25]([OH:34])[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

참가 물질

반응물 2

HCID 2474Bupivacaine (USAN:INN:BAN)3회

HCID 5816Epinephrine

생성물 1

HCID 9294Ephedrine

실험 절차

Microspheres containing bupivacaine loaded to about 75 percent by weight with bupivacaine are prepared, in a percent loading of about 0.05 percent, by weight, using the methods described in EXAMPLES 1-3 or EXAMPLES 4-9, above. In addition, microspheres containing added epinephrine, in a percent loadings of 0.001 percent, 0.05 percent and 1 percent, without bupivacaine, are also prepared according to EXAMPLES 1-3 or EXAMPLES 4-9, above.

후처리

customare prepared, in a percent loading of about 0.05 percent, by weight
additionIn addition, microspheres containing

출처 및 근거

ORD 기록: ord-4287cf64a9934602815a1f2ffdeebfa7
출처 데이터셋: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06514516B1

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