(R)-2-azido-1-benzylethylamine → (2R)-3-Phenylpropane-1,2-diamine

HRID 1057295

반응식

HRID 1057295 반응식
[N:1]([CH2:4][C@H:5]([NH2:13])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[N+]=[N-]>C(O)C.[Pd]>[NH2:1][CH2:4][C@H:5]([NH2:13])[CH2:6][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

참가 물질

4

반응물 1

HCID 14802497(R)-2-azido-1-benzylethylamine

생성물 1

HCID 12699299(2R)-3-Phenylpropane-1,2-diamine

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A sample of the compound from step 4 (1.2 g, 6.8 mmol) is hydrogenated (4 atm) in ethanol over 1.2 g of 10% Pd/C for 21.5 hours at room temperature. The mixture is filtered to remove the catalyst, and the solvent is removed to afford the title compound.

후처리

  1. customfor 21.5 hours
  2. customat room temperature
  3. filtrationThe mixture is filtered
  4. customto remove the catalyst
  5. customthe solvent is removed

출처 및 근거

ORD 기록
ord-0469f3e95c63410db270f6aafc3f1542
출처 데이터셋
uspto-grants-2003_02
특허 번호
US06514944B2

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