Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(2-Bromoethoxy)tetrahydro-2H-pyran → 1-(2-Hydroxyethyl)-4-(4-methyl-5-isoquinolyl)aminopiperidine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(2-Bromoethoxy)tetrahydro-2H-pyran | HCID 86621 | — |
| 반응물 | 4-Methyl-N-(piperidin-4-YL)isoquinolin-5-amine hydrochloride | HCID 21979810 | — |
| 생성물 | 1-(2-Hydroxyethyl)-4-(4-methyl-5-isoquinolyl)aminopiperidine hydrochloride | HCID 21979983 | — |
반응 단계
According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 106 to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07094789B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-d00bddfa7b8a4ef6b23783ff72234805 |
| 출처 메모 | uspto-grants-2006_08 |