4-Fluoro-3-(trifluoromethyl)benzaldehyde → 4-[(4-Methylphenyl)thio]-3-(trifluoromethyl)benzaldehyde

반응식

F[C:2]1[C:9]([C:10]([F:13])([F:12])[F:11])=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.BrC1C=CC([S:23][C:24]2[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][CH:25]=2)=C(C=1)C=O>>[CH3:30][C:27]1[CH:28]=[CH:29][C:24]([S:23][C:2]2[CH:3]=[CH:4][C:5]([CH:6]=[O:7])=[CH:8][C:9]=2[C:10]([F:13])([F:12])[F:11])=[CH:25][CH:26]=1

참가 물질

반응물 2

HCID 5222694-Fluoro-3-(trifluoromethyl)benzaldehyde

HCID 18668950Benzaldehyde, 5-bromo-2-[(4-methylphenyl)thio]-

생성물 1

HCID 186689164-[(4-Methylphenyl)thio]-3-(trifluoromethyl)benzaldehyde수율 100%

실험 절차

Using 4-fluoro-5-(trifluoromethyl)benzaldehyde (0.20 g, 1.0 mmol), 4-[(4-methylphenyl)thio]-3-(trifluoromethyl)benzaldehyde (0.30 g, 100%) was obtained in a manner similar to the synthesis of 5-bromo-2-[(4-methylphenyl)thio]benzaldehyde.

출처 및 근거

ORD 기록: ord-20520e0cebd84c84af7f8a2eff6f70dc
출처 데이터셋: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06518268B1

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