2-(2-Bromoethoxy)tetrahydro-2H-pyran → HCID 178418815, 화합물

HRID 10587

반응식

HRID 10587 반응식
Br[CH2:2][CH2:3][O:4]C1CCCCO1.[ClH:11].[CH:12]1[C:21]2[C:16](=[C:17]([NH:22][C@H:23]3[CH2:28][CH2:27][C@@H:26]([NH2:29])[CH2:25][CH2:24]3)[CH:18]=[CH:19][CH:20]=2)[CH:15]=[CH:14][N:13]=1>>[ClH:11].[CH:12]1[C:21]2[C:16](=[C:17]([NH:22][C@H:23]3[CH2:24][CH2:25][C@@H:26]([NH:29][CH2:2][CH2:3][OH:4])[CH2:27][CH2:28]3)[CH:18]=[CH:19][CH:20]=2)[CH:15]=[CH:14][N:13]=1

참가 물질

3

반응물 2

HCID 866212-(2-Bromoethoxy)tetrahydro-2H-pyranHCID 178418692HCID 178418692, 화합물

생성물 1

HCID 178418815HCID 178418815, 화합물

실험 절차

According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 23 to obtain the title compound.

후처리

  1. customa deprotection reaction

출처 및 근거

ORD 기록
ord-f848c0cd70984334a629a40bca364c48
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07094789B2

연결된 노트

불러오는 중…