2-(2-Bromoethoxy)tetrahydro-2H-pyran → HCID 178418834, 화합물

HRID 10588

반응식

HRID 10588 반응식
Br[CH2:2][CH2:3][O:4]C1CCCCO1.[ClH:11].[CH3:12][C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][C:21]=2[NH:23][C@H:24]2[CH2:29][CH2:28][C@@H:27]([NH2:30])[CH2:26][CH2:25]2)[CH:16]=[N:15][CH:14]=1>>[ClH:11].[CH3:12][C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][C:21]=2[NH:23][C@H:24]2[CH2:29][CH2:28][C@@H:27]([NH:30][CH2:2][CH2:3][OH:4])[CH2:26][CH2:25]2)[CH:16]=[N:15][CH:14]=1

참가 물질

3

반응물 2

HCID 866212-(2-Bromoethoxy)tetrahydro-2H-pyranHCID 178419091HCID 178419091, 화합물

생성물 1

HCID 178418834HCID 178418834, 화합물

실험 절차

According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 120 to obtain the title compound.

후처리

  1. customa deprotection reaction

출처 및 근거

ORD 기록
ord-aa44ef0c05ad4a6ba243340aa196d0e5
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07094789B2

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