2-(2-Bromoethoxy)tetrahydro-2H-pyran → HCID 178418917, 화합물

HRID 10589

반응식

HRID 10589 반응식
Br[CH2:2][CH2:3][O:4]C1CCCCO1.[ClH:11].[C:12]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][C:22]=2[O:24][C@H:25]2[CH2:30][CH2:29][C@H:28]([NH2:31])[CH2:27][CH2:26]2)[CH:17]=[N:16][CH:15]=1)#[N:13]>>[ClH:11].[C:12]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][C:22]=2[O:24][C@H:25]2[CH2:30][CH2:29][C@H:28]([NH:31][CH2:2][CH2:3][OH:4])[CH2:27][CH2:26]2)[CH:17]=[N:16][CH:15]=1)#[N:13]

참가 물질

3

반응물 2

HCID 866212-(2-Bromoethoxy)tetrahydro-2H-pyranHCID 178419076HCID 178419076, 화합물

생성물 1

HCID 178418917HCID 178418917, 화합물

실험 절차

According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 134 to obtain the title compound.

후처리

  1. customa deprotection reaction

출처 및 근거

ORD 기록
ord-d229cb2de4d94ee3acd656b3de7ca16d
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07094789B2

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