Pyridinium chloride → HCID 178450100, 화합물

HRID 1059138노트

반응식

HRID 1059138 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([C:19]3[N:20]=[CH:21][N:22](C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)[CH:23]=3)([OH:18])[CH:15]([CH3:17])[CH3:16])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.Cl.N1C=CC=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[CH:10][C:11]([C:14]([C:19]3[N:20]=[CH:21][NH:22][CH:23]=3)([OH:18])[CH:15]([CH3:17])[CH3:16])=[CH:12][CH:13]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 10176127Pyridinium chlorideHCID 120433891-(4'-chloro[1,1'-biphenyl]-4-yl)-1-(1-trityl-1H-imidazol-4-yl)-2-methyl-1-propanol

생성물 1

HCID 178450100HCID 178450100, 화합물수율 68.5%

실험 절차

By the reaction in the same manner as in Example 4-(iii) using 1-(4′-chloro[1,1′-biphenyl]-4-yl)-1-(1-trityl-1H-imidazol-4-yl)-2-methyl-1-propanol (3.00 g) and pyridine hydrochloride (1.04 g), the title compound (1.18 g) was obtained as colorless plate crystals.

후처리

  1. customBy the reaction in the same manner as in Example

출처 및 근거

ORD 기록
ord-456960dad873419db8b388dda9d83f0f
출처 데이터셋
uspto-grants-2003_02
특허 번호
US06518257B1

반응 노트

불러오는 중…