Pyridinium chloride → HCID 178450129, 화합물

반응식

[CH3:1][CH:2]([CH3:41])[C:3]([C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][N:36]=2)[CH:30]=1)([C:5]1[N:6]=[CH:7][N:8](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:9]=1)[OH:4].Cl.N1C=CC=CC=1>>[NH:8]1[CH:9]=[C:5]([C:3]([C:29]2[CH:34]=[CH:33][CH:32]=[C:31]([C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][N:36]=3)[CH:30]=2)([OH:4])[CH:2]([CH3:1])[CH3:41])[N:6]=[CH:7]1

참가 물질

반응물 2

HCID 10176127Pyridinium chloride

HCID 186685632-methyl-1-[3-(2-pyridyl)phenyl]-1-(1-trityl-1H-imidazol-4-yl)-1-propanol

생성물 1

HCID 178450129HCID 178450129, 화합물수율 68.3%

실험 절차

By the reaction in the same manner as in Example 4-(iii) using 2-methyl-1-[3-(2-pyridyl)phenyl]-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (527 mg), pyridine hydrochloride (205 mg), the title compound (197 mg) was obtained as colorless plate crystals.

후처리

customBy the reaction in the same manner as in Example

출처 및 근거

ORD 기록: ord-5bacfe7b3eed43d19bbf2f3b92ea8135
출처 데이터셋: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06518257B1

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