2-Benzyl-5-nitropyridine → 6-Benzylpyridin-3-amine
반응식
[CH2:1]([C:8]1[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(OCC)(=O)C.[C].[Pd]>[CH2:1]([C:8]1[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][N:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
4
실험 절차
389 mg of 2-benzyl-5-nitropyridine was dissolved in ethyl acetate and 153 mg of 10% palladium carbon was added thereto. Then the resulting mixture was stirred under a hydrogen gas stream at room temperature under atmospheric pressure for 30 minutes. Then the reaction mixture was filtered through celite. After distilling off the solvent under reduced pressure, 333 mg of the title compound was obtained as an amber oily substance.
후처리
- filtrationThen the reaction mixture was filtered through celite
- distillationAfter distilling off the solvent under reduced pressure
출처 및 근거
- ORD 기록
- ord-3d90a3f3768d4c6cad00aa16c8f3f118
- 출처 데이터셋
- uspto-grants-2003_02
- 특허 번호
- US06518423B1
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