3-(3-Trifluoromethylpyridin-2-yl)nitrobenzene → HCID 18631012, 화합물
반응식
[F:1][C:2]([F:19])([F:18])[C:3]1[C:4]([C:9]2[CH:10]=[C:11]([N+:15]([O-])=O)[CH:12]=[CH:13][CH:14]=2)=[N:5][CH:6]=[CH:7][CH:8]=1>C(O)C.[Pd]>[F:19][C:2]([F:1])([F:18])[C:3]1[C:4]([C:9]2[CH:10]=[C:11]([CH:12]=[CH:13][CH:14]=2)[NH2:15])=[N:5][CH:6]=[CH:7][CH:8]=1참가 물질
4
실험 절차
A suspension of 3-(3-trifluoromethylpyridin-2-yl)nitrobenzene (500 mg) in ethanol (10 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 167 mg) under a hydrogen atmosphere for 2 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(3-trifluoromethylpyridin-2-yl)aniline (425 mg).
후처리
- filtrationThe catalyst was filtered off
- customthe filtrate was evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-8facb9c335e74fc6a195e8f2f741e7fc
- 출처 데이터셋
- uspto-grants-2003_02
- 특허 번호
- US06521643B1
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