(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid → 3-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

반응식

[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:24])[O:9][CH:10]([c:13]3[c:14]([I:23])[cH:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]3)[CH:11]2[CH3:12])[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1)([F:32])[F:33].[F:34][c:35]1[cH:36][c:37]([O:47][CH3:48])[c:38]([B:44]([OH:45])[OH:46])[cH:39][c:40]1[CH:41]([CH3:42])[CH3:43]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:24])[O:9][CH:10]([c:13]3[c:14](-[c:38]4[c:37]([O:47][CH3:48])[cH:36][c:35]([F:34])[c:40]([CH:41]([CH3:42])[CH3:43])[cH:39]4)[cH:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]3)[CH:11]2[CH3:12])[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1)([F:32])[F:33]

참가 물질

반응물 2

HCID 53363739(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid

HCID 178422006CID 76598413

생성물 1

HCID 1784929413-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

출처 및 근거

ORD 기록: ord-5984258d05ed465eacced70ccd7ab847
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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