2,5-Dibromohydroquinone → 2,5-Dibromo-1,4-benzoquinone

HRID 1060618노트

반응식

HRID 1060618 반응식
[Br:1][C:2]1[CH:8]=[C:7]([OH:9])[C:6]([Br:10])=[CH:5][C:3]=1[OH:4].[N+]([O-])([O-])=O.[NH4+].[Ce]>C(#N)C.O>[Br:1][C:2]1[C:3](=[O:4])[CH:5]=[C:6]([Br:10])[C:7](=[O:9])[CH:8]=1

참가 물질

5

반응물 2

HCID 2809452,5-DibromohydroquinoneHCID 57418452Ammonium cerium-nitrate

생성물 1

HCID 5430932,5-Dibromo-1,4-benzoquinone수율 71%

시약·촉매·용매 2

HCID 962Water용매HCID 6342Acetonitrile용매

실험 절차

To a solution of 2,5-dibromohydroquinone (1) (5 g, 18.6 mol) in acetonitrile (250 ml) was added cerium ammonium nitrate (21.4 g, 39.0 mmol), in small portions. The clear orange solution was stirred for 10 min at room temperature, diluted with water (80 ml) and extracted with chloroform (3×200 ml). The combined chloroform layers were dried over sodium sulphate and evaporated, yielding 3.5 g (71%) of the quinone (2).

후처리

  1. extractionextracted with chloroform (3×200 ml)
  2. dry with materialThe combined chloroform layers were dried over sodium sulphate
  3. customevaporated

출처 및 근거

ORD 기록
ord-58327378666747f79ea504e3e98fc7d5
출처 데이터셋
uspto-grants-2003_02
특허 번호
US06525063B2

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