Dichloromethane → 3-(3-Chloro-2-fluorophenyl)pyrrolidin-3-ol

HRID 106080

반응식

[Cl:1][c:2]1[c:3]([F:21])[c:4]([C:8]2([OH:20])[CH2:9][N:10]([C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[CH2:11][CH2:12]2)[cH:5][cH:6][cH:7]1.[Cl:29][CH2:30][Cl:31].[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[Cl:1][c:2]1[c:3]([F:21])[c:4]([C:8]2([OH:20])[CH2:9][NH:10][CH2:11][CH2:12]2)[cH:5][cH:6][cH:7]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 67404349Tert-butyl 3-(3-chloro-2-fluorophenyl)-3-hydroxypyrrolidine-1-carboxylate

생성물 1

HCID 685157443-(3-Chloro-2-fluorophenyl)pyrrolidin-3-ol

출처 및 근거

ORD 기록: ord-1ff60f07dbab4989887269663e39cb77
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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