Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(Butylamino)acetonitrile → N-Butyl-N-(cyanomethyl)-4-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (Butylamino)acetonitrile | HCID 76373 | — |
| 반응물 | 4-(1,4-Dioxa-8-aza-spiro[4.5]dec-8-yl)-benzoic acid | HCID 15948425 | — |
| 생성물 | N-Butyl-N-(cyanomethyl)-4-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)benzamide | HCID 22220389 | — |
반응 단계
The title compound was prepared from 4-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-benzoic acid (which was obtained in Example 150) (0.37 g, 1.4 mmol) and (n-butylamino)acetonitrile (0.48 g, 4.2 mmol) according to the procedure shown for Example 154 to give 0.52 g of an amber gum; MS (ES) m/z: 358.3 (MH+); HRMS (ES) Calcd. for C20H28N3O3 (MH+): 358.2125, Found: 358.2120.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06525202B2 |
| 출처 데이터셋 | uspto-grants-2003_02 |
| ORD ID | ord-a341565257bf478d98daa966afe87904 |
| 출처 메모 | uspto-grants-2003_02 |