HCID 22285048, 화합물 → HCID 178458159, 화합물

HRID 1061895노트

반응식

HRID 1061895 반응식
Br[C:2]1[CH:16]=[CH:15][C:5]2[C:6]3[CH2:7][N:8]([CH3:14])[C:9](=[O:13])[C:10]=3[CH:11]=[CH:12][C:4]=2[CH:3]=1.C([N:36]1[CH:40]=[C:39]([C:41](=[O:44])[CH2:42][CH3:43])[N:38]=[CH:37]1)(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>>[OH:44][C:41]([C:2]1[CH:16]=[CH:15][C:5]2[C:6]3[CH2:7][N:8]([CH3:14])[C:9](=[O:13])[C:10]=3[CH:11]=[CH:12][C:4]=2[CH:3]=1)([C:39]1[N:38]=[CH:37][NH:36][CH:40]=1)[CH2:42][CH3:43]

참가 물질

3

반응물 2

HCID 22285048HCID 22285048, 화합물HCID 222850567-bromo-2-methyl-1,2-dihydro-3H-benzo[e]isoindol-3-one

생성물 1

HCID 178458159HCID 178458159, 화합물수율 67.1%

실험 절차

By the reaction in the same manner as in Example 18 using 7-bromo-2-methyl-1,2-dihydro-3H-benzo[e]isoindol-3-one (0.14 g) and 1-(1-trityl-1H-imidazol-4-yl)-1-propanone (0.17 g), the title compound (0.10 g) was obtained.

출처 및 근거

ORD 기록
ord-19e0e263b2264cc08e047d17e638fc12
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06960586B2

반응 노트

불러오는 중…