tert-Butyl N-[4-(4-chlorophenyl)-2-nitro-phenyl]carbamate → tert-butyl N-[2-amino-4-(4-chlorophenyl)phenyl]carbamate

HRID 1061960

반응식

HRID 1061960 반응식
[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[N+:21]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Zn].[NH4+].[Cl-]>[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:15]=[CH:16][C:17]([Cl:20])=[CH:18][CH:19]=2)=[CH:10][C:9]=1[NH2:21])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 1

HCID 69592790tert-Butyl N-[4-(4-chlorophenyl)-2-nitro-phenyl]carbamate

생성물 1

HCID 69592781tert-butyl N-[2-amino-4-(4-chlorophenyl)phenyl]carbamate

시약·촉매·용매 1

HCID 5362536Azanium ZINC chloride촉매

실험 절차

Prepared from (4′-chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example C2) by reduction with Zn/NH4Cl according to the general procedure G (method c). Obtained as a green solid (162 mg).

출처 및 근거

ORD 기록
ord-045c2758688a45df94f450972aca3dd9
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06960578B2

연결된 노트

불러오는 중…