Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile → {2-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4-thiophen-3-yl-phenyl}-carbamic acid tert.-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile | HCID 11736337 | — |
| 반응물 | Tert-butyl [2-amino-4-(3-thienyl)phenyl]carbamate | HCID 57717476 | — |
| 생성물 | {2-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4-thiophen-3-yl-phenyl}-carbamic acid tert.-butyl ester | HCID 86588082 | — |
반응 단계
Prepared from (2-amino-4-thiophen-3-yl-phenyl)-carbamic acid tert.-butyl ester (Example G6) and 3-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile (Example J4) according to the general procedure K. Obtained as a brown solid (104 mg) and used crude in the next step (Example 7).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06960578B2 |
| 출처 데이터셋 | uspto-grants-2005_11 |
| ORD ID | ord-0bb1e5ecfe024e58a01bb3dbf0f17be9 |
| 출처 메모 | uspto-grants-2005_11 |