1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, methyl ester → 1H-Pyrrolo[3,2-b]pyridine-2-carbaldehyde

HRID 1062699노트

반응식

HRID 1062699 반응식
[NH:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[C:10](OC)=[O:11]>[O-2].[Mn+2]>[NH:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[CH:10]=[O:11]

참가 물질

3

반응물 1

HCID 222817761H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, methyl ester

생성물 1

HCID 222817391H-Pyrrolo[3,2-b]pyridine-2-carbaldehyde

시약·촉매·용매 1

HCID 160959Manganese oxide촉매

실험 절차

This was prepared from methyl 1H-pyrrolo[3,2-b]pyridin-2-carboxylate (0.1 g) and amine (1d) by the method of Example 16c, (except that the alcohol was stirred with manganese (II) oxide overnight) and used without purification.

후처리

  1. customused without purification

출처 및 근거

ORD 기록
ord-4f1d990a173f4523b09763a9a1a3854c
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06962917B2

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