2-Bromoethyl ethyl ether → 3-(2-ethoxyethoxy)-1-methyl-4-(4-methylphenyl)-1H-pyrazol-5-ylamine

반응식

[NH2:1][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([OH:8])[C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=1.[CH2:16]([O:18][CH2:19][CH2:20]Br)[CH3:17]>>[CH2:16]([O:18][CH2:19][CH2:20][O:8][C:4]1[C:3]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)=[C:2]([NH2:1])[N:6]([CH3:7])[N:5]=1)[CH3:17]

참가 물질

반응물 2

HCID 611412-Bromoethyl ethyl ether

HCID 1784239155-amino-1-methyl-4-(4-methylphenyl)-1H-pyrazol-3-ol

생성물 1

HCID 234003133-(2-ethoxyethoxy)-1-methyl-4-(4-methylphenyl)-1H-pyrazol-5-ylamine

실험 절차

The method of Preparation 37 was used to prepare the title compound from 5-amino-1-methyl-4-(4-methylphenyl)-1H-pyrazol-3-ol (Preparation 3a) and 2-bromoethyl ethyl ether.

후처리

customThe method of Preparation 37

출처 및 근거

ORD 기록: ord-126fe11564ce4a7096404f5bea9c56de
출처 데이터셋: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06962923B2

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