3-Nitrophenylboronic Acid → HCID 86584908, 화합물

HRID 1062979

반응식

HRID 1062979 반응식
I[C:2]1[C:10]2[S:9][C:8]([NH:11][C:12]([C:14]3[S:15][C:16]([CH3:19])=[CH:17][CH:18]=3)=[O:13])=[N:7][C:6]=2[C:5]([O:20][CH3:21])=[CH:4][CH:3]=1.[N+:22]([C:25]1[CH:26]=[C:27](B(O)O)[CH:28]=[CH:29][CH:30]=1)([O-:24])=[O:23]>>[N+:22]([C:25]1[CH:30]=[C:29]([C:2]2[C:10]3[S:9][C:8]([NH:11][C:12]([C:14]4[S:15][C:16]([CH3:19])=[CH:17][CH:18]=4)=[O:13])=[N:7][C:6]=3[C:5]([O:20][CH3:21])=[CH:4][CH:3]=2)[CH:28]=[CH:27][CH:26]=1)([O-:24])=[O:23]

참가 물질

3

반응물 2

HCID 16773-Nitrophenylboronic AcidHCID 865849065-Methyl-thiophene-2-carboxylic acid (4-methoxy-7-iodo-benzothiazol-2-yl)-amide

생성물 1

HCID 86584908HCID 86584908, 화합물수율 42%

실험 절차

5-Methyl-thiophene-2-carboxylic acid [7-(3-nitro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide is synthesized from 5-methyl-thiophene-2-carboxylic acid (7-iodo-4-methoxy-benzothiazol-2-yl)-amide (155 mg, 0.36 mmol) and 3-nitrophenylboronic acid (135 mg, 0.81 mmol) using the general procedure A as a light yellow crystalls in 42% yield. MS: m/e=425 (M+).

출처 및 근거

ORD 기록
ord-347ea0ca33ac413283ada8ae74d85d0a
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06963000B2

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