HCID 22173110, 화합물 → HCID 10178832, 화합물

HRID 1062984

반응식

HRID 1062984 반응식
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:13]([C:15]3[S:16][C:17]([CH3:20])=[CH:18][CH:19]=3)=[O:14])[S:11][C:7]=2[C:6](I)=[CH:5][CH:4]=1.C[Sn](C)(C)[C:24]1[CH:25]=[C:26]([NH2:30])[CH:27]=[CH:28][CH:29]=1>>[NH2:30][C:26]1[CH:25]=[C:24]([C:6]2[C:7]3[S:11][C:10]([NH:12][C:13]([C:15]4[S:16][C:17]([CH3:20])=[CH:18][CH:19]=4)=[O:14])=[N:9][C:8]=3[C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[CH:29]=[CH:28][CH:27]=1

참가 물질

3

반응물 2

HCID 22173110HCID 22173110, 화합물HCID 865849065-Methyl-thiophene-2-carboxylic acid (4-methoxy-7-iodo-benzothiazol-2-yl)-amide

생성물 1

HCID 10178832HCID 10178832, 화합물수율 56%

실험 절차

5-Methyl-thiophene-2-carboxylic acid [7-(3-amino-phenyl)-4-methoxy-benzothiazol-2-yl]-amide is synthesized from 5-methyl-thiophene-2-carboxylic acid (4-methoxy-7-iodo-benzothiazol-2-yl)-amide (300 mg, 0.70 mmol) and 3-trimethylstannanyl-phenylamine (291 mg, 1.14 mmol) using the general procedure B as a light brown solid in 56% yield. MS: m/e=396 (M+H+).

출처 및 근거

ORD 기록
ord-8bf4bd45cfc749b48b4a0d3634f0e046
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06963000B2

연결된 노트

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