Methanesulfonyl chloride → HCID 91069034, 화합물

반응식

[CH3:1][S:2](Cl)(=[O:4])=[O:3].[CH3:6][NH:7][CH:8]1[CH2:12][CH2:11][N:10]([C:13]([C:15]2[S:23][C:22]3[C:17](=[N:18][CH:19]=[CH:20][C:21]=3[Cl:24])[CH:16]=2)=[O:14])[CH2:9]1>>[CH3:6][N:7]([CH:8]1[CH2:12][CH2:11][N:10]([C:13]([C:15]2[S:23][C:22]3[C:17](=[N:18][CH:19]=[CH:20][C:21]=3[Cl:24])[CH:16]=2)=[O:14])[CH2:9]1)[S:2]([CH3:1])(=[O:4])=[O:3]

참가 물질

반응물 2

HCID 31297Methanesulfonyl chloride

HCID 22278671HCID 22278671, 화합물

생성물 1

HCID 91069034HCID 91069034, 화합물

실험 절차

The title compound was prepared from methanesulfonyl chloride and (3-methylamino-pyrrolidin-1-yl)-(7-chloro-thieno[3,2-b]pyridin-2yl)-methanone by a procedure analogous to Example 64C. MS: 374/376 (MH+); HPLC Rf: 4.14 min.; HPLC purity 98%.

출처 및 근거

ORD 기록: ord-0239a8708837472299e3542913a5d2a7
출처 데이터셋: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06964961B2

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