Acetyl chloride → N-[1-(Diphenylmethyl)-3-azetidinyl]acetamide

반응식

[CH:1]([N:14]1[CH2:17][CH:16]([NH2:18])[CH2:15]1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:19](Cl)(=[O:21])[CH3:20]>>[CH:1]([N:14]1[CH2:17][CH:16]([NH:18][C:19](=[O:21])[CH3:20])[CH2:15]1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 6367Acetyl chloride

HCID 57445463-Amino-1-(diphenylmethyl)azetidine

생성물 1

HCID 13495841N-[1-(Diphenylmethyl)-3-azetidinyl]acetamide

실험 절차

The title compound was prepared from 1-benzhydryl-azetidin-3-ylamine and acetyl chloride by a procedure analogous to Example 70A. MS: 281 (MH+); HPLC Rf: 5.57 min; HPLC purity: 93%.

출처 및 근거

ORD 기록: ord-55a6dcc0299845e19693ba5993716908
출처 데이터셋: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06964961B2

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