4-Benzyloxybenzyl chloride → [4-(4-Benzyloxy-benzylsulfanyl)-2-methyl-phenoxy]-acetic acid

반응식

Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][CH:4]=1.C[O:18][C:19](=[O:30])[CH2:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([SH:28])=[CH:24][C:23]=1[CH3:29]>>[CH2:10]([O:9][C:6]1[CH:7]=[CH:8][C:3]([CH2:2][S:28][C:25]2[CH:26]=[CH:27][C:22]([O:21][CH2:20][C:19]([OH:30])=[O:18])=[C:23]([CH3:29])[CH:24]=2)=[CH:4][CH:5]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

참가 물질

반응물 2

HCID 700424-Benzyloxybenzyl chloride

HCID 20770797Methyl (2-methyl-4-sulfanylphenoxy)acetate

생성물 1

HCID 22280002[4-(4-Benzyloxy-benzylsulfanyl)-2-methyl-phenoxy]-acetic acid

실험 절차

The title compound was prepared in the manner analogous to Example 1F using 1-chloromethyl-4-benzyloxy-benzene and 2C. MS m/z 409 (M+1).

출처 및 근거

ORD 기록: ord-069d7fa30d894b3e9ffdffa0b287306c
출처 데이터셋: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06964983B2

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