4'-(Trifluoromethyl)[1,1'-biphenyl]-3-methanol → [7-(4'-Trifluoromethyl-biphenyl-3-ylmethylsulfanyl)-indan-4-yloxy]-acetic Acid
반응식
FC(F)(F)C1C=CC(C2C=CC=C(CO)C=2)=CC=1.C[O:20][C:21](=[O:51])[CH2:22][O:23][C:24]1[CH:32]=[CH:31][C:30]([S:33][CH2:34][C:35]2[CH:36]=[C:37]([C:41]3[CH:46]=[CH:45][C:44]([C:47]([F:50])([F:49])[F:48])=[CH:43][CH:42]=3)[CH:38]=[CH:39][CH:40]=2)=[C:29]2[C:25]=1[CH2:26][CH2:27][CH2:28]2>>[F:50][C:47]([F:48])([F:49])[C:44]1[CH:45]=[CH:46][C:41]([C:37]2[CH:38]=[CH:39][CH:40]=[C:35]([CH2:34][S:33][C:30]3[CH:31]=[CH:32][C:24]([O:23][CH2:22][C:21]([OH:51])=[O:20])=[C:25]4[C:29]=3[CH2:28][CH2:27][CH2:26]4)[CH:36]=2)=[CH:42][CH:43]=1참가 물질
3
실험 절차
The title compound was prepared in the manner analogous to Example 3B using 48A. MS m/z 236 (M+1-Cl). Step 3. Preparation of [7-(4′-Trifluoromethyl-biphenyl-3-ylmethylsulfanyl)-indan-4-yloxy]-acetic acid methyl ester (Compound 48C)
출처 및 근거
- ORD 기록
- ord-f780a82d8fff4ee7b8b4cdba02318bf0
- 출처 데이터셋