3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazole → {7-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethylsulfanyl]-indan-4-yloxy}-acetic Acid
반응식
Cl[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=2)[O:5][N:4]=1.C[O:16][C:17](=[O:30])[CH2:18][O:19][C:20]1[CH:28]=[CH:27][C:26]([SH:29])=[C:25]2[C:21]=1[CH2:22][CH2:23][CH2:24]2>>[Cl:14][C:11]1[CH:12]=[CH:13][C:8]([C:6]2[O:5][N:4]=[C:3]([CH2:2][S:29][C:26]3[CH:27]=[CH:28][C:20]([O:19][CH2:18][C:17]([OH:30])=[O:16])=[C:21]4[C:25]=3[CH2:24][CH2:23][CH2:22]4)[CH:7]=2)=[CH:9][CH:10]=1참가 물질
3
실험 절차
The title compound was prepared in the manner analogous to Example 1F using 3-chloromethyl-5-(4-chloro-phenyl)-isoxazole and 12C. mp 112-114° C.; MS m/z 430 (M+1).
출처 및 근거
- ORD 기록
- ord-8cad9c38b5ee401f92a0c76eb6d813e4
- 출처 데이터셋
- uspto-grants-2005_11
- 특허 번호