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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 10638생성일: 2026년 10월 25일

4-Acetylbenzoic Acid → 4-[3E-(2,4-Dimethoxy-5-pyrimidin-5-yl-phenyl)-acryloyl]-benzoic acid

https://huagongshe.com/reaction/10638

반응식

참여 물질

역할이름HCID투입량
반응물4-Acetylbenzoic AcidHCID 11470—
반응물2,4-Dimethoxy-5-pyrimidin-5-yl-benzaldehydeHCID 21980989—
생성물4-[3E-(2,4-Dimethoxy-5-pyrimidin-5-yl-phenyl)-acryloyl]-benzoic acidHCID 2104161326%

반응 단계

The title compound was prepared by condensing 2,4-dimethoxy-5-pyrimidin-5-yl-benzaldehyde (Ex-31A) and 4-acetylbezoic acid in a similar manner as described in Ex-3. Yellow solid, mp>260° C., 26% yield. 1H-NMR (DMSO-d6) δ 9.11 (s, 1H), 8.96 (s, 2H), 8.13–8.16 (m, 3H), 8.01–8.09 (m, 3H), 7.90 (d, J=15 Hz, 1H), 6.85 (s, 1H), 3.99 (s, 3H), MS m/z=391 ([M+H]+, 100%). HRMS (ES+) Calcd. for C22H18N2O5: 391.1294. Found: 391.1295.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07094801B2
출처 데이터셋uspto-grants-2006_08
ORD IDord-9c3dc3b392cd4438ba117a73b6f01262
출처 메모uspto-grants-2006_08