3-Methoxy-2-nitrobenzaldehyde → 3-Hydroxy-2-nitrobenzaldehyde
반응식
C[O:2][C:3]1[C:4]([N+:11]([O-:13])=[O:12])=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=[O:7].B(Br)(Br)Br.C(Cl)Cl>C(Cl)Cl>[OH:2][C:3]1[C:4]([N+:11]([O-:13])=[O:12])=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=[O:7]참가 물질
4
반응 조건
- 온도
- 0 °C
실험 절차
3.62 g of 3-methoxy-2-nitrobenzaldehyde was dissolved in 80 ml of methylene chloride and a boron tribromide-methylene chloride solution (15.03 g of, boron tribromide, 40 ml of methylene chloride) was added dropwise under ice cooling, followed by stirring at 0° C. for one hour. The reaction solution was poured into ice, extracted with chloroform, dried and then concentrated to obtain 3.32 g of the desired compound.
후처리
- additionThe reaction solution was poured into ice
- extractionextracted with chloroform
- customdried
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-2e23ae38f1fa4ffa9f0519f295d4f484
- 출처 데이터셋
- uspto-grants-2005_11
- 특허 번호
- US06967211B2
반응 노트
불러오는 중…