Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-(Pyridin-4-yl)propanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 2-Acetamidodibenzothiophene | HCID 108627 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(Pyridin-4-yl)propanoic acid | HCID 233243 | — |
반응 단계
To a solution of ethyl 3-pyridin-4-ylpropanoate (Method 2; 103.1 g, 576 mmol) in water (400 ml) and ethanol (20 ml) at room temperature was added potassium hydroxide (60 g, 1600 mmol). After 18 hours hydrochloric acid (100 ml) was added to give a white solid. Yield 62.8 g (73%). NMR 8.38 (d, 2H), 7.21 (d, 2H), 2.70 (t, 2H), 2.52 (t, 2H); m/z 152.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06967216B2 |
| 출처 데이터셋 | uspto-grants-2005_11 |
| ORD ID | ord-50519d7a41d24d5cb0afee1d39e0f1aa |
| 출처 메모 | uspto-grants-2005_11 |