Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Acetylbenzoic acid → 2-[3E-(2,4-Dimethoxy-5-thiophen-2-yl-phenyl)-acryloyl]-benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Acetylbenzoic acid | HCID 68474 | — |
| 반응물 | 2,4-Dimethoxy-5-thien-2-ylbenzaldehyde | HCID 16116183 | — |
| 생성물 | 2-[3E-(2,4-Dimethoxy-5-thiophen-2-yl-phenyl)-acryloyl]-benzoic acid | HCID 16115759 | 47% |
반응 단계
The title compound was prepared by condensing 2,4-dimethoxy-5-(thiophen-2-yl)-benzaldehyde (Ex-6A) and 2-acetylbenzoic acid in a similar manner as described in Ex-3. Yellow solid, 47% yield, mp 196–198° C. 1H-NMR (DMSO-d6) δ 8.00 (s, 1H), 7.84 (d, 1H), 7.61 (m, 3H), 7.45 (m, 3H), 7.21 (d, 1H), 7.08 (t, 1H), 6.75 (s, 1H), 3.95 (s, 3H), 3.86 (s, 3H). MS m/z=394 ([M]+, 100%). Anal. calculated for C22H18O5S: C, 66.99; H, 4.60; S, 8.13. found C, 67.08; H, 4.17; S, 7.97.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07094801B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-83a7ca9901c148adb3f76c7c46b13cc9 |
| 출처 메모 | uspto-grants-2006_08 |