Chloroacetyl chloride → 2-Chloro-N-(2-oxo-2,3-dihydro-1H-indol-4-yl)acetamide

반응식

[NH2:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][C:5](=[O:11])[NH:6]2.[Cl:12][CH2:13][C:14](Cl)=[O:15]>>[Cl:12][CH2:13][C:14]([NH:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][C:5](=[O:11])[NH:6]2)=[O:15]

참가 물질

반응물 2

HCID 6577Chloroacetyl chloride

HCID 122374724-Aminoindolin-2-one

생성물 1

HCID 222733972-Chloro-N-(2-oxo-2,3-dihydro-1H-indol-4-yl)acetamide

실험 절차

The subtitle compound was prepared from 4-amino-oxindole (0.19 g) (J. Org. Chem., 1983, 48 (15), 2468-72) and chloroacetyl chloride (0.1 ml) by the method of Example 15 step (i). Yield: 0.25 g

출처 및 근거

ORD 기록: ord-20a32be6b28042559c15607bb7bff461
출처 데이터셋: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06969713B2

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