Dimethylformamide → 4-(Benzyloxy)-2-fluorobenzaldehyde
반응식
Br[C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][C:3]=1[F:16].[Li]CCCC.CN(C)[CH:24]=[O:25]>O1CCCC1>[CH2:9]([O:8][C:5]1[CH:6]=[CH:7][C:2]([CH:24]=[O:25])=[C:3]([F:16])[CH:4]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1참가 물질
5
실험 절차
In analogy to the procedure described in example 8 c], 1-bromo-2-fluoro-4-(phenylmethoxy)-benzene was treated with n-BuLi and N,N-dimethylformamide in dry tetrahydrofuran to yield 4-benzyloxy-2-fluoro-benzaldehyde as off-white crystals.
출처 및 근거
- ORD 기록
- ord-bb2a7ece302542ef907d33b610b6f4fc
- 출처 데이터셋
- uspto-grants-2005_11
- 특허 번호
- US06969725B2
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