4-[2-(4-Methylphenyl)ethoxy]phenylcarbamyl chloride → 4-(4-Methylphenethyloxy)phenyl isocyanate

HRID 1065043노트

반응식

HRID 1065043 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][O:10][C:11]2[CH:16]=[CH:15][C:14]([NH:17][C:18](Cl)=[O:19])=[CH:13][CH:12]=2)=[CH:4][CH:3]=1>C1(C)C=CC=CC=1>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][O:10][C:11]2[CH:16]=[CH:15][C:14]([N:17]=[C:18]=[O:19])=[CH:13][CH:12]=2)=[CH:6][CH:7]=1

참가 물질

3

반응물 1

HCID 130176574-[2-(4-Methylphenyl)ethoxy]phenylcarbamyl chloride

생성물 1

HCID 130176584-(4-Methylphenethyloxy)phenyl isocyanate수율 94.8%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

A solution of 4-[2-(4-methylphenyl)ethoxy]phenylcarbamyl chloride (IV) (14.4 g, 0.05 mole) in toluene (80 ml) was heated at 60° C. for 1 hour and distilled under reduced pressure to obtain 12 g of 4-[2-(4-methylphenyl)-ethoxy]phenyl isocyanate (III) as white crystals (yield, 94.9%). B.P., 170°-181° C./0.9 mmHg.

후처리

  1. distillationdistilled under reduced pressure
  2. customto obtain

출처 및 근거

ORD 기록
ord-18d76d3662994d7887ca39457289ef9a
출처 데이터셋
uspto-grants-1982_05
특허 번호
US04328166

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