HCID 12899697, 화합물 → HCID 20277153, 화합물
반응식
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[CH2:3][CH:2]2[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1.[H][H]>[Pd].C(O)C>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[CH2:8][N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1참가 물질
5
실험 절차
A mixture of 1-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)imidazole (2.0 g, 11.48 mmol) and palladium on charcoal (0.2 g, 10%) in dry ethanol was shaken in an atmosphere of hydrogen for 4.5 h. The reaction mixture was then filtered through Hyflo-Supercel, and the filtrate was concentrated under reduced pressure to afford a colourless oil. Distillation of the oil afforded 1-(bicyclo[2.2.1]heptan-2-ylmethyl)imidazole as a colourless oil, b.p. 82°-84°/0.15 mm Hg.
후처리
- filtrationThe reaction mixture was then filtered through Hyflo-Supercel
- concentrationthe filtrate was concentrated under reduced pressure
- customto afford a colourless oil
- distillationDistillation of the oil
출처 및 근거
- ORD 기록
- ord-444a0b7921a8422b93ebb71b6ecfcb52
- 출처 데이터셋
- uspto-grants-1982_05
- 특허 번호
- US04328234
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