6-(4-Bromobutoxy)-3,4-dihydro-carbostyril → 6-[4-(2-Quinolyl-mercapto)-butoxy]-3,4-dihydro-carbostyril

반응식

Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH2:11][CH2:10]2.[SH:18][C:19]1[CH:28]=[CH:27][C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[N:20]=1>>[N:20]1[C:21]2[C:26](=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:27]=[CH:28][C:19]=1[S:18][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH2:11][CH2:10]2

참가 물질

반응물 2

HCID 131098086-(4-Bromobutoxy)-3,4-dihydro-carbostyril

HCID 178418736HCID 178418736, 화합물

생성물 1

HCID 205400526-[4-(2-Quinolyl-mercapto)-butoxy]-3,4-dihydro-carbostyril

실험 절차

Prepared analogous to Example 1 from 6-(4-bromobutoxy)-3,4-dihydro-carbostyril (m.p. 142°-147° C.) and 2-mercapto-quinoline.

출처 및 근거

ORD 기록: ord-010d79f4cffc4efebd225903de02566d
출처 데이터셋: uspto-grants-1982_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04329347

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