2,6-Dihydroxy-4-methylquinoline → 4-Methyl-6-(4-phenylsulfonyl-butoxy)-carbostyril

HRID 1065404노트

반응식

HRID 1065404 반응식
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[NH:5][C:4](=[O:13])[CH:3]=1.[C:14]1([S:20]([CH2:23][CH2:24][CH2:25][CH2:26]Br)(=[O:22])=[O:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH2:26][CH2:25][CH2:24][CH2:23][S:20]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)(=[O:21])=[O:22])[CH:10]=2)[NH:5][C:4](=[O:13])[CH:3]=1

참가 물질

3

반응물 2

HCID 6002882,6-Dihydroxy-4-methylquinolineHCID 114827894-Phenylsulfonylbutyl bromide

생성물 1

HCID 205399904-Methyl-6-(4-phenylsulfonyl-butoxy)-carbostyril

실험 절차

Prepared analogous to Example 140 from 4-methyl-6-hydroxy-carbostyril (m.p. 326°-330° C.) and 4-phenylsulfonyl-butyl-bromide.

출처 및 근거

ORD 기록
ord-55e96be5283840f4a2eaa50de58b6e7c
출처 데이터셋
uspto-grants-1982_05
특허 번호
US04329347

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