4-Methyl-6-(4-bromo-butoxy)-carbostyril → 4-Methyl-6-[4-(2-quinolyl-mercapto)-butoxy]-carbostyril

반응식

[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16]Br)[CH:10]=2)[NH:5][C:4](=[O:18])[CH:3]=1.[SH:19][C:20]1[CH:29]=[CH:28][C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[N:21]=1>>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][S:19][C:20]3[CH:29]=[CH:28][C:27]4[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=4)[N:21]=3)[CH:10]=2)[NH:5][C:4](=[O:18])[CH:3]=1

참가 물질

반응물 2

HCID 205401234-Methyl-6-(4-bromo-butoxy)-carbostyril

HCID 178418736HCID 178418736, 화합물

생성물 1

HCID 205400764-Methyl-6-[4-(2-quinolyl-mercapto)-butoxy]-carbostyril

실험 절차

Prepared analogous to Example 122 from 4-methyl-6-(4-bromo-butoxy)-carbostyril and 2-mercapto-quinoline.

출처 및 근거

ORD 기록: ord-3bd47c8f5b6641af96381720a8c288d2
출처 데이터셋: uspto-grants-1982_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04329347

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