Chlorosulfonic acid → 3,5-Dichloro-2,4,6-trifluorobenzoyl fluoride

HRID 1065601노트

반응식

HRID 1065601 반응식
[Cl:1][C:2]1[C:3]([F:15])=[C:4]([C:11](F)(F)[F:12])[C:5]([F:10])=[C:6]([Cl:9])[C:7]=1[F:8].ClS(O)(=O)=[O:18]>>[Cl:1][C:2]1[C:3]([F:15])=[C:4]([C:5]([F:10])=[C:6]([Cl:9])[C:7]=1[F:8])[C:11]([F:12])=[O:18]

참가 물질

3

반응물 2

HCID 24638Chlorosulfonic acidHCID 27825101,3-dichloro-2,4,6-trifluoro-5-(trifluoromethyl)benzene

생성물 1

HCID 198504823,5-Dichloro-2,4,6-trifluorobenzoyl fluoride수율 82.1%

실험 절차

A mixture of 520 g of 3,5-dichloro-2,4,6-trifluorobenzotrifluoride and 400 g of chlorosulphonic acid is heated for 4 hours, whilst stirring, as described in Example 1. 392 g of 3,5-dichloro-2,4,6-trifluorobenzoyl fluoride (82% of the theoretical yield) of boiling point 90° to 95° C./15 mbars and nD20 :1.5007 are obtained by distillation.

후처리

  1. temperatureis heated for 4 hours

출처 및 근거

ORD 기록
ord-43b5a139636340b7928a54e2774ec4c2
출처 데이터셋
uspto-grants-1982_05
특허 번호
US04330366

반응 노트

불러오는 중…