trans-N-Decyl-2-(4-nitrophenyl)cyclopropanecarboxamide → trans-N-Decyl-2-(4-aminophenyl)cyclopropanecarboxamide

HRID 1065828

반응식

HRID 1065828 반응식
[CH2:1]([NH:11][C:12]([C@@H:14]1[CH2:16][C@H:15]1[C:17]1[CH:22]=[CH:21][C:20]([N+:23]([O-])=O)=[CH:19][CH:18]=1)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>C(O)(=O)C.[Fe]>[CH2:1]([NH:11][C:12]([C@@H:14]1[CH2:16][C@H:15]1[C:17]1[CH:22]=[CH:21][C:20]([NH2:23])=[CH:19][CH:18]=1)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

4

반응물 1

HCID 12854652trans-N-Decyl-2-(4-nitrophenyl)cyclopropanecarboxamide

생성물 1

HCID 54265967trans-N-Decyl-2-(4-aminophenyl)cyclopropanecarboxamide수율 87%

시약·촉매·용매 2

HCID 23925Iron촉매HCID 176Acetic Acid용매

실험 절차

The title compound was prepared in 87% yield by reducing trans-N-decyl-2-(4-nitrophenyl)cyclopropanecarboxamide with iron powder in glacial acetic acid, in a manner analogous to Preparation 34.

후처리

  1. customin a manner analogous to Preparation 34

출처 및 근거

ORD 기록
ord-a1007ef6eac9454fa4d9772a068d42bf
출처 데이터셋
uspto-grants-1982_05
특허 번호
US04331683

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